Athlete's Foot Research Today is a free monthly online journal that collates and summarizes the latest research about Athlete's Foot, including details on tinea, causes, treatment, prevention.

Discovery of a new boron-containing antifungal agent, 5-fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the potential treatment of onychomycosis.

Baker SJ, Zhang YK, Akama T, Lau A, Zhou H, Hernandez V, Mao W, Alley MR, Sanders V, Plattner JJ

Anacor Pharmaceuticals Inc., 1060 East Meadow Circle, Palo Alto, California 94303, USA. sbaker@anacor.com

A structure-activity relationship investigation for a more efficacious therapy to treat onychomycosis, a fungal infection of the toe and fingernails, led to the discovery of a boron-containing small molecule, 5-fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2690), which is currently in clinical trials for onychomycosis topical treatment.

Published 20 July 2006 in J Med Chem, 49(15): 4447-50.
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